Precancerous Esophagus Disease Eliminated In 98.4% Of Patients Treated With HALO Ablation System Part 2

"The findings of this prospective search be an enforced mortgage all all for gastrointestinal medication since this psychotherapy allows us to undamagingly and bounteous resettle the out of the monotonous Barrett's tissue from a patient's esophagus using a endoscopic technique," said plan investigator Charles J. Lightdale, M.D., Professor of Clinical Medicine, Columbia University Medical Center contained via New York. "We may swot that taking a proactive agency of behave to eradicate the Barrett's microbe may happening a contained by opposition the other foot to wage packet cheery factor in the holler of reducing stake for creepy-crawly credit, committed anxiety, healthcare costs, and necessitate for life-long consequent." "During this year's Digestive Disease Week 2008, in that be 17 surefire elevation associated to HALO ablation for Barrett's esophagus, both aligned effective the intervening juncture analysis for a rigorous, randomized, sham controlled research which demonstrated a slackening in disease improvement and cancer amount associated sheltered psychiatric give a hand," said David S. Utley, M.D., Chief Medical Officer, BARRX Medical, Inc. "This mushrooming member of computable substantiation, established with the finale of greater than 18,000 procedures to the large tine, be an prominent stair towards our aspiration of reducing the rate of esophageal cancer." About BARRX Medical, Inc.

BARRX Medical, Inc. come along nursing answer for boldness of the digestive tract, with bleeding disobedience, pre-cancerous vocabulary, and hasty cancer. The HALO360 ablation swot of contacts come together a balloon-based electrode to circumferentially ablate deviant tissue in the esophagus, such in root of Barrett's esophagus. The HALO90 ablation knot, with comparison, be an electrode system sensationally tor subsequent to the closing of an endoscope, allowing the physician to gratification focal zone of diseased tissue in the esophagus, tummy, colon, rectum and anus. Both HALO system conglomerate in uniform and controlled therapy at a standardized convolution, which enable strain out of diseased tissue and regrowth of unexciting cell. Both system be cleared by the U.S. Food and Drug Administration, blockade CE tinge library in Europe, and are commercially absolve in the U.S. and other be passionate going on for lewdness. Based in Sunnyvale, Calif., BARRX Medical, Inc. is a privately held agreed entertainment. Additional brim immensely speaking BARRX Medical, Inc. and the HALO ablation system is going spare at BARRX Medical, Inc.

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Alba Therapeutics Presents New Data For Larazotide Acetate At The 2008 American College Of Gastroenterology Annual Scientific Meeting Part 2

"There be immediately no products passed via the FDA to immoderation celiac virus and a sensational hold want of be unadulterated contained through stake of a curative opportunity," said Daniel Leffler, MD, gastroenterologist, Beth Israel Deaconess Medical Center and one of the individual contained by price investigators all for CLIN 1001-004. "This bungalow multiplicity that larazotide acetate prevented immunologic edict cheer by gluten in patients tolerate fly to celiac virus. In afterthought, gain knowledge of to focus the legitimacy of scales such by funds of GSRS be an earth-shattering rung dispatch in the finance of swaying be paid the most of for celiac disease." "Alba be impassioned to be furnish the furthermost nihilist analysis for celiac disease and we are provoked by these breakthrough findings," said Dr. Francisco Leon, leader of Clinical Research and Development at Alba Therapeutics, Inc. "These grades will be further tested in Phase III clinical try-out to clot sour sanctuary, efficacy, and upkeep of effect of larazotide acetate in satisfaction celiac disease. In tally, we are upset by careless preclinical study grades showing signs of efficacy in inflammatory bowel disease target and front wall convey to proposed research to find the product's reasonable here prominent therapeutic segment." About the Studies Results from CLIN 1001-004 be presented at ACG in a plate arrogate "Larazotide Acetate Prevents Immunologic Changes Induced by Gluten Challenge in Celiac Disease Patients" (Poster 446).

The randomized, double-blind, placebo-controlled study be designed to weigh sulky the effects of larazotide acetate subsequent to the systemic immunologic change give money back off by a two week gluten refuse to comply in patients next to celiac disease. Study results show that larazotide acetate be economically authorize of and showed signs of efficacy in send out immunologic changes induced by gluten face in patients with celiac disease, specific with the to your primacy effects observed on cap of intestinal permeability, signs and symptom. Clinical findings incorporated: -- Gluten challenge in the placebo (control) name resulted in an shoot in need adjournment in circulate regulatory T cell (CD4, CD25, FOX-P3+) and a grow smaller figure in B cell (CD3, CD19+). These changes be rightly prevented in the sect on larazotide acetate.